Biotin Rat Anti-Mouse Ly-6A/E Antibody (S-3835)
SKU: 24234046598

Biotin Rat Anti-Mouse Ly-6A/E Antibody (S-3835)

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Description

Biotin Rat Anti-Mouse Ly-6A/E Antibody (S-3835)Product Specification Host Rat Antigen Ly 6A E Synonyms Lymphocyte antigen 6A 2 6E 1; Ly 6A. 2 Ly 6E. 1; Stem cell antigen 1 (SCA 1); T cell activating protein (TAP) Location Cell membrane Accession P05533Q64253 Clone Number S 3835 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS

Product Specification


Host Rat
Antigen Ly-6A/E
Synonyms Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Stem cell antigen 1 (SCA-1); T-cell-activating protein (TAP)
Location Cell membrane
Accession P05533、Q64253
Clone Number S-3835
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

Ly-6A/E, also known as Sca-1 (stem cell antigen-1), is an 18-kDa glycosylphosphatidylinositol (GPI)-anchored cell surface protein belonging to the murine Ly-6 multigene family, predominantly expressed on multipotent hematopoietic stem cells in adult mouse bone marrow and fetal liver, and is widely used as a marker for isolating these stem cells; beyond its stem cell association, Ly-6A/E is upregulated on activated T and B lymphocytes and appears to participate in T-cell receptor-mediated activation, myoblast proliferation and differentiation, bone formation, and interferon-induced immune responses, with expression levels varying between mouse strains carrying different Ly-6 haplotypes.

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SKU: 24234046598

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